The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer.

ABSTRACT: Breast cancer is a common malignancy with the highest mortality rate among women worldwide. Its incidence is on the rise year after year, accounting for more than one-tenth of new cancers worldwide. Increasing evidence suggests that forkhead box (FOX) transcription factors play an important role in the occurrence and development of breast cancer. However, little is known about the relationship between the expression, prognostic value, function, and immune infiltration of FOX transcription factors in tumor microenvironment. We used bioinformatics to investigate expression and function of FOX factor in breast cancer. Our results revealed the expression levels of FOXA1 and FOXM1 were significantly higher in breast cancer tissues than in normal tissues. The high expression of mRNA in FOXA1 (P 

SUBMITTER: Yuan H 

PROVIDER: S-EPMC11018205 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature