Hypotension during intensive care stay and mortality and morbidity: a systematic review and meta-analysis.

ABSTRACT:

Purpose

The aim of this study is to provide a summary of the existing literature on the association between hypotension during intensive care unit (ICU) stay and mortality and morbidity, and to assess whether there is an exposure-severity relationship between hypotension exposure and patient outcomes.

Methods

CENTRAL, Embase, and PubMed were searched up to October 2022 for articles that reported an association between hypotension during ICU stay and at least one of the 11 predefined outcomes. Two independent reviewers extracted the data and assessed the risk of bias. Results were gathered in a summary table and studies designed to investigate the hypotension-outcome relationship were included in the meta-analyses.

Results

A total of 122 studies (176,329 patients) were

SUBMITTER: Schuurmans J 

PROVIDER: S-EPMC11018652 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature