Resurgence of respiratory syncytial virus with dominance of RSV-B during the 2022-2023 season.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) is a common cause of upper and lower respiratory tract infections. This study aimed to explore the prevalence of respiratory syncytial virus (RSV) and other respiratory viruses in Bulgaria, characterize the genetic diversity of RSV strains, and perform amino acid sequence analyses of RSV surface and internal proteins.

Methods

Clinical and epidemiological data and nasopharyngeal swabs were prospectively collected from patients with acute respiratory infections between October 2020 and May 2023. Real-time PCR for 13 respiratory viruses, whole-genome sequencing, phylogenetic, and amino acid analyses were performed.

Results

This study included three epidemic seasons (2020-2021, 2021-2022, and 2022-2023) from week 40 of the prev

SUBMITTER: Korsun N 

PROVIDER: S-EPMC11019023 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature