It is time to explore the impact of length of gestation and fetal health on the human lifespan.

ABSTRACT: A recently proposed principal law of lifespan (PLOSP) proposes to extend the whole human lifespan by elongating different life stages. As the preborn stage of a human being, gestation is the foundation for the healthy development of the human body. The antagonistic pleiotropy (AP) theory of aging states that there is a trade-off between early life fitness and late-life mortality. The question is whether slower development during the gestation period would be associated with a longer lifespan. Among all living creatures, the length of the gestation period is highly positively correlated to the length of the lifespan, although such a correlation is thought to be influenced by the body sizes of different species. While examining the relationship between lifespan length and body size within th

SUBMITTER: Yu Z 

PROVIDER: S-EPMC11019132 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature