Biomarkers associated with cardiovascular disease in women with spontaneous preterm birth: A case-control study.

ABSTRACT:

Introduction

Women with spontaneous preterm birth have an increased risk of cardiovascular disease later in life. Studies suggest potential pathophysiological mechanisms in common, but whether these could be identified by measurement of soluble circulating protein biomarkers in women with spontaneous preterm birth is unknown. The aim of this study was to determine if protein biomarkers associated with cardiovascular disease distinguish women with spontaneous preterm birth from healthy controls, both at pregnancy and at follow up.

Material and methods

Study participants were identified in the population-based Uppsala biobank of pregnant women in Sweden, where plasma samples were collected in mid-pregnancy. In a first screening phase, we identified participants who subsequentl

SUBMITTER: Cederlof ET 

PROVIDER: S-EPMC11019525 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature