Previous cancers in women diagnosed with premature ovarian insufficiency: A nationwide population-based case-control study.

ABSTRACT:

Introduction

To investigate the occurrence of previous cancer diagnoses in women suffering from premature ovarian insufficiency (POI) and compare it with the general population, shedding light on the association between cancer, cancer treatments, and POI.

Material and methods

We conducted a nationwide case-control study based on registry data from various sources, including the Social Insurance Institution, Finnish Population Information System, and Finnish Cancer Registry spanning from 1953 to 2018. Our participants comprised all women in Finland who, between 1988 and 2017, received hormone replacement therapy reimbursement for ovarian insufficiency before the age of 40 years (n = 5221). Controls, matched in terms of age and municipality of residence, were selected from the

SUBMITTER: Silven H 

PROVIDER: S-EPMC11019530 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature