Peptide Dendrimer-Based Antibacterial Agents: Synthesis and Applications.

ABSTRACT: Pathogenic bacteria cause the deaths of millions of people every year. With the development of antibiotics, hundreds and thousands of people's lives have been saved. Nevertheless, bacteria can develop resistance to antibiotics, rendering them insensitive to antibiotics over time. Peptides containing specific amino acids can be used as antibacterial agents; however, they can be easily degraded by proteases in vivo. To address these issues, branched peptide dendrimers are now being considered as good antibacterial agents due to their high efficacy, resistance to protease degradation, and low cytotoxicity. The ease with which peptide dendrimers can be synthesized and modified makes them accessible for use in various biological and nonbiological fields. That is, peptide dendrimers hold

SUBMITTER: Paul S 

PROVIDER: S-EPMC11019562 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature