Characterization of genital chlamydia trachomatis infection among women attending infertility and gynecology clinics in Hunan, China.

ABSTRACT:

Background

Genital infection with Chlamydia trachomatis (C. trachomatis) is a major public health issue worldwide. It can lead to cervicitis, urethritis, and infertility. This study was conducted to determine the characteristics of genital C. trachomatis infection among women attending to the infertility and gynecology clinics.

Methods

Endocervical swabs were collected from 8,221 women for C. trachomatis nucleotide screening and genotyping, while serum samples were collected for C. trachomatis pgp3 antibody determination using luciferase immunosorbent assays.

Results

High C. trachomatis DNA prevalence (3.76%) and seroprevalence (47.46%) rates were found, with genotype E (27.5%) being the most prevalent. C. trachomatis omp1 sense mutation was associated with cervical i

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC11020174 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature