Central Body Fat Distribution and Kidney Function after Living Kidney Donation.

ABSTRACT:

Background

In most screening guidelines, high body mass index (BMI) is considered a contraindication for kidney donation. New insights suggest that central body fat distribution might provide greater power in assessing kidney risk. This study aimed to determine whether BMI and central body fat distribution measures are associated with long-term kidney function after donor nephrectomy. We hypothesized that higher BMI, waist circumference (WC), and waist-to-height ratio (WHtR) were associated with lower kidney function long term after donation.

Methods

The study population consisted of living kidney donors. BMI, WC, and WHtR were measured during donor screening. The outcome postdonation kidney function was assessed using measured GFR (mGFR) (mGFR, 125 I-iothalamate infusion) a

SUBMITTER: Westenberg LB 

PROVIDER: S-EPMC11020429 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature