Targeted metabolomic profiles of serum amino acids are independently correlated with malnutrition in older adults.

ABSTRACT:

Background

Malnutrition is a common geriatric syndrome that is closely associated with adverse clinical outcomes and poses significant harm to older adults. Early assessment of nutritional status plays a crucial role in preventing and intervening in cases of malnutrition. However, there is currently a lack of measurable methods and biomarkers to evaluate malnutrition in older adults accurately. The aim of this study is to investigate the independent correlation between serum levels of amino acids and malnutrition in older adults, and to identify effective metabolomics biomarkers that can aid in the early detection of geriatric malnutrition.

Methods

A total of 254 geriatric medical examination participants from Beijing Hospital were included in the study, consisting of 182 in

SUBMITTER: Zhao X 

PROVIDER: S-EPMC11020810 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature