Predicting Major Adverse Events in Patients Undergoing Transcatheter Left Atrial Appendage Occlusion.

ABSTRACT:

Background

The National Cardiovascular Data Registry Left Atrial Appendage Occlusion Registry (LAAO) includes the vast majority of transcatheter LAAO procedures performed in the United States. The objective of this study was to develop a model predicting adverse events among patients undergoing LAAO with Watchman FLX.

Methods

Data from 41 001 LAAO procedures with Watchman FLX from July 2020 to September 2021 were used to develop and validate a model predicting in-hospital major adverse events. Randomly selected development (70%, n=28 530) and validation (30%, n=12 471) cohorts were analyzed with 1000 bootstrapped samples, using forward stepwise logistic regression to create the final model. A simplified bedside risk score was also developed using this model.

Results

I

SUBMITTER: Faridi KF 

PROVIDER: S-EPMC11021146 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature