Treatments and Outcomes Among Patients with Sydenham Chorea: A Meta-Analysis.

ABSTRACT:

Importance

Sydenham chorea is the most common acquired chorea of childhood worldwide; however, treatment is limited by a lack of high-quality evidence.

Objectives

To evaluate historical changes in the clinical characteristics of Sydenham chorea and identify clinical and treatment factors at disease onset associated with chorea duration, relapsing disease course, and functional outcome.

Data sources

The systematic search for this meta-analysis was conducted in PubMed, Embase, CINAHL, Cochrane Library, and LILACS databases and registers of clinical trials from inception to November 1, 2022 (search terms: [Sydenham OR Sydenham's OR rheumatic OR minor] AND chorea).

Study selection

Published articles that included patients with a final diagnosis of Sydenham chorea (

SUBMITTER: Eyre M 

PROVIDER: S-EPMC11022117 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature