Schema therapy versus treatment as usual for outpatients with difficult-to-treat depression: study protocol for a parallel group randomized clinical trial (DEPRE-ST).

ABSTRACT:

Background

About one third of patients with depression are in a condition that can be termed as "difficult-to-treat". Some evidence suggests that difficult-to-treat depression is associated with a higher frequency of childhood trauma and comorbid personality disorders or accentuated features. However, the condition is understudied, and the effects of psychotherapy for difficult-to-treat depression are currently uncertain. The aim of this trial is to investigate the beneficial and harmful effects of 30 sessions of individual schema therapy versus treatment as usual for difficult-to-treat depression in the Danish secondary, public mental health sector.

Methods

In this randomized, multi-centre, parallel-group, superiority clinical trial, 129 outpatients with difficult-to-treat

SUBMITTER: Arendt ITP 

PROVIDER: S-EPMC11022394 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature