Atypical brain structural connectivity and social cognition in childhood maltreatment and peer victimisation.

ABSTRACT:

Background

Childhood maltreatment (CM) is associated with neurobiological aberrations and atypical social cognition. Few studies have examined the neural effects of another common early-life interpersonal stressor, namely peer victimisation (PV). This study examines the associations between tract aberrations and childhood interpersonal stress from caregivers (CM) and peers (PV), and explores how the observed tract alterations are in turn related to affective theory of mind (ToM).

Methods

Data from 107 age-and gender-matched youths (34 CM [age = 19.9 ± 1.68; 36%male], 35 PV [age = 19.9 ± 1.65; 43%male], 38 comparison subjects [age = 20.0 ± 1.66; 42%male] were analysed using tractography and whole-brain tract-based spatial statistics (TBSS).

Results

At the whole-brain l

SUBMITTER: Lim L 

PROVIDER: S-EPMC11022413 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature