Spatial Relationships in the Tumor Microenvironment Demonstrate Association with Pathologic Response to Neoadjuvant Chemoimmunotherapy in Muscle-invasive Bladder Cancer.

ABSTRACT:

Background

Platinum-based neoadjuvant chemotherapy (NAC) is standard for patients with muscle-invasive bladder cancer (MIBC). Pathologic response (complete: ypT0N0 and partial: ObjectiveUsing the NanoString GeoMx platform, we performed proteomic digital spatial profiling (DSP) on transurethral resections of bladder tumors from 18 responders (

SUBMITTER: Beckabir W 

PROVIDER: S-EPMC11022933 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature