Incidence and survival of pediatric and adult hepatocellular carcinoma, United States, 2001-2020.

ABSTRACT:

Importance

Hepatocellular carcinoma accounts for approximately 80% of liver neoplasms. Globally, hepatocellular carcinoma ranks as the third most lethal cancer, with the number of deaths expected to further increase by 2040. In adults, disparities in incidence and survival are well described while pediatric epidemiology is not well characterized.

Objective

To describe incidence and survival for pediatric (ages 0-19 years) hepatocellular carcinoma cases and compare these measures to adults (ages ≥20 years) diagnosed with hepatocellular carcinoma. We evaluated demographic factors and clinical characteristics that influence incidence and outcomes.

Design

Population-based cohort study.

Setting

Incidence data from the US Cancer Statistics database from 2003 to 2020

SUBMITTER: Arnett A 

PROVIDER: S-EPMC11023662 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature