Alkyl quinolones mediate heterogeneous colony biofilm architecture that improves community-level survival.

ABSTRACT: Bacterial communities exhibit complex self-organization that contributes to their survival. To better understand the molecules that contribute to transforming a small number of cells into a heterogeneous surface biofilm community, we studied acellular aggregates, structures seen by light microscopy in Pseudomonas aeruginosa colony biofilms using light microscopy and chemical imaging. These structures differ from cellular aggregates, cohesive clusters of cells important for biofilm formation, in that they are visually distinct from cells using light microscopy and are reliant on metabolites for assembly. To investigate how these structures benefit a biofilm community we characterized three recurrent types of acellular aggregates with distinct geometries that were each abundant in spe

SUBMITTER: Weaver AA 

PROVIDER: S-EPMC11025328 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature