Cardiometabolic and immune response to exercise training in patients with metabolic syndrome: retrospective analysis of two randomized clinical trials.

ABSTRACT:

Background

Metabolic syndrome (MetS) is defined by the presence of central obesity plus ≥two metabolic/cardiovascular risk factors (RF), with inflammation being a major disease-driving mechanism. Structured endurance exercise training (ET) may positively affect these traits, as well as cardiorespiratory fitness (V̇O₂peak).

Aims

We explore individual ET-mediated improvements of MetS-associated RF in relation to improvements in V̇O₂peak and inflammatory profile.

Methods

MetS patients from two randomized controlled trials, ExMET (n = 24) and OptimEx (n = 34), had performed 4- or 3-months supervised ET programs according to the respective trial protocol. V̇O₂peak, MetS-defining RFs (both RCTs), broad blood leukocyte profile,

SUBMITTER: Lechner K 

PROVIDER: S-EPMC11025358 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature