Use of Quantitative CT Imaging to Identify Bronchial Thermoplasty Responders.

ABSTRACT:

Background

Bronchial thermoplasty (BT) is a treatment for patients with poorly controlled, severe asthma. However, predictors of treatment response to BT are defined poorly.

Research question

Do baseline radiographic and clinical characteristics exist that predict response to BT?

Study design and methods

We conducted a longitudinal prospective cohort study of participants with severe asthma receiving BT across eight academic medical centers. Participants received three separate BT treatments and were monitored at 3-month intervals for 1 year after BT. Similar to prior studies, a positive response to BT was defined as either improvement in Asthma Control Test results of ≥ 3 or Asthma Quality of Life Questionnaire of ≥ 0.5. Regression analyses were used to evaluate the

SUBMITTER: Samant M 

PROVIDER: S-EPMC11026166 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature