Role of non-contrast CT component of prostate-specific membrane antigen PET/CT scan in the detection of peripheral zone prostate cancer.

ABSTRACT:

Objective

The aim of this study was to look for feasibility of non-contrast CT (NCCT) in detecting peripheral zone prostate cancer (PCa).

Methods

A retrospective analysis included 50 biopsy-proven PCa patients between April 2019 and March 2022 who underwent staging whole body prostate-specific membrane antigen (PSMA)/CT prior to treatment. The control subjects were 50 randomly selected adult male patients who underwent PET/CT for non-prostate malignancy during the same time period. Two readers independently calculated the Hounsfield unit (HU) of normal peripheral zone, central zone, and corresponding PSMA avid focus in cases.

Results

No significant difference was seen in the mean HU value of normal peripheral zone between cases and controls. Significant difference in

SUBMITTER: Aggarwal P 

PROVIDER: S-EPMC11027233 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature