Affective Symptoms in Pregnancy are Associated with the Vaginal Microbiome.

ABSTRACT: Composition of the vaginal microbiome in pregnancy is associated with adverse maternal, obstetric, and child health outcomes. Identifying the sources of individual differences in the vaginal microbiome is therefore of considerable clinical and public health interest. The current study tested the hypothesis that vaginal microbiome composition during pregnancy is associated with an individual's experience of affective symptoms and stress exposure. Data were based on a prospective longitudinal study of a diverse and medically healthy community sample of 275 mother-infant pairs. Affective symptoms and stress exposure and select measures of associated biomarkers (diurnal salivary cortisol, serum measures of sex hormones) were collected at each trimester; self-report, clinical, and medical recor

SUBMITTER: Scheible K 

PROVIDER: S-EPMC11030453 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature