GenoMycAnalyzer: a web-based tool for species and drug resistance prediction for Mycobacterium genomes.

ABSTRACT:

Background

Drug-resistant tuberculosis (TB) is a major threat to global public health. Whole-genome sequencing (WGS) is a useful tool for species identification and drug resistance prediction, and many clinical laboratories are transitioning to WGS as a routine diagnostic tool. However, user-friendly and high-confidence automated bioinformatics tools are needed to rapidly identify M. tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM), detect drug resistance, and further guide treatment options.

Results

We developed GenoMycAnalyzer, a web-based software that integrates functions for identifying MTBC and NTM species, lineage and spoligotype prediction, variant calling, annotation, drug-resistance determination, and data visualization. The accuracy of GenoMycAna

SUBMITTER: Kim D 

PROVIDER: S-EPMC11031912 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature