Speckle-tracking global longitudinal strain predicts death and cardiovascular events in patients with systemic sclerosis.

ABSTRACT:

Aims

Albeit often asymptomatic, heart involvement in systemic sclerosis (SSc) represents a negative prognostic factor, accounting for nearly one-fourth of all deaths. Global longitudinal strain (GLS) is accurate in detecting heart involvement in patients with SSc and no overt cardiac disease and allows early detection and longitudinal monitoring, but its association with clinical endpoints has not been tested so far. The primary outcome was the association between left and right GLS and mortality for all causes. The secondary outcome was the association between left and right GLS and hospitalizations.

Methods and results

A prospective longitudinal study enrolling all consecutive patients with SSc without structural heart disease or previous cardiovascular event.A total of 16

SUBMITTER: Stronati G 

PROVIDER: S-EPMC11032194 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature