Bioactive O^N^O^ Schiff base appended homoleptic titanium(iv) complexes: DFT, BSA/CT-DNA interactions, molecular docking and antitumor activity against HeLa and A549 cell lines.

ABSTRACT: Five new homoleptic derivatives of titanium(iv) have been developed and characterized by physicochemical techniques. Metal complexes, TiH₂L¹ [(C₃₈H₂₆N₆O₄)Ti], TiH₂L² [(C₃₈H₂₄F₂N₆O₄)Ti], TiH₂L³ [(C₃₈H₂₄Cl₂N₆O₄)Ti], TiH₂L⁴ [(C₃₈H₂₄Br₂N₆O₄)Ti] and TiH₂L⁵ [(C₃₈H₂₄N₈O₈)Ti], were obtained by treating Ti(OPrⁱ)₄ with appropriate ONO ligands (H₂L¹-H₂L⁵) in anhydrous THF as solv

SUBMITTER: Thanigachalam S 

PROVIDER: S-EPMC11034360 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature