The impact of phage and phage resistance on microbial community dynamics.

ABSTRACT: Where there are bacteria, there will be bacteriophages. These viruses are known to be important players in shaping the wider microbial community in which they are embedded, with potential implications for human health. On the other hand, bacteria possess a range of distinct immune mechanisms that provide protection against bacteriophages, including the mutation or complete loss of the phage receptor, and CRISPR-Cas adaptive immunity. While our previous work showed how a microbial community may impact phage resistance evolution, little is known about the inverse, namely how interactions between phages and these different phage resistance mechanisms affect the wider microbial community in which they are embedded. Here, we conducted a 10-day, fully factorial evolution experiment to examine ho

SUBMITTER: Alseth EO 

PROVIDER: S-EPMC11034675 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature