Patient Selection for Living Donor Liver Transplantation in Acute-on-chronic Liver Failure.

ABSTRACT:

Background and objectives

Acute-on-chronic liver failure (ACLF) is associated with high short-term mortality without liver transplantation (LT). The selection criteria for LT in these patients are not well defined. The objective of this study was to determine factors associated with post-transplant survival in ACLF.

Methods

This was a single-center retrospective study of patients who underwent living donor liver transplantation (LDLT) for ACLF between 2012 and 2022. Out of 1093 transplants, 110 patients had underlying ACLF, based on the European Association for the Study of the Liver-Chronic Liver Failure Consortium (EASL-CLIF) criteria. We looked at factors associated with 1-year posttransplant survival.

Results

The median model for end-stage liver disease (MELD) sco

SUBMITTER: Bhatti ABH 

PROVIDER: S-EPMC11036089 | biostudies-literature | 2024 Sep-Oct

REPOSITORIES: biostudies-literature