Next-generation sequencing survey of acute febrile illness in Senegal (2020-2022).

ABSTRACT:

Introduction

Acute febrile illnesses (AFI) in developing tropical and sub-tropical nations are challenging to diagnose due to the numerous causes and non-specific symptoms. The proliferation of rapid diagnostic testing and successful control campaigns against malaria have revealed that non-Plasmodium pathogens still contribute significantly to AFI burden. Thus, a more complete understanding of local trends and potential causes is important for selecting the correct treatment course, which in turn will reduce morbidity and mortality. Next-generation sequencing (NGS) in a laboratory setting can be used to identify known and novel pathogens in individuals with AFI.

Methods

In this study, plasma was collected from 228 febrile patients tested negative for malaria at clinic

SUBMITTER: Orf GS 

PROVIDER: S-EPMC11037400 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature