The interleukin-17 gene of herpesvirus saimiri.

ABSTRACT: In comparison to wild-type herpesvirus saimiri, viral interleukin-17 gene knockout mutants have unaltered behavior regarding viral replication, T-cell transformation in vitro, and pathogenicity in cottontop tamarins. Thus, this gene is not required for T-cell lymphoma induction but may contribute to apathogenic viral persistence in the natural host, the squirrel monkey.

SUBMITTER: Knappe A 

PROVIDER: S-EPMC110381 | biostudies-literature | 1998 Jul

REPOSITORIES: biostudies-literature