Isolation, characterisation and description of the roseoflavin producer Streptomyces berlinensis sp. nov.

ABSTRACT: The Gram-positive bacteria Streptomyces davaonensis and Streptomyces cinnabarinus have been the only organisms known to produce roseoflavin, a riboflavin (vitamin B₂) derived red antibiotic. Using a selective growth medium and a phenotypic screening, we were able to isolate a novel roseoflavin producer from a German soil sample. The isolation procedure was repeated twice, that is, the same strain could be isolated from the same location in Berlin 6 months and 12 months after its first isolation. Whole genome sequencing of the novel roseoflavin producer revealed an unusual chromosomal arrangement and the deposited genome sequence of the new isolate (G + C content of 71.47%) contains 897 genes per inverted terminal repeat, 6190 genes in the core and 107 genes located on an illegit

SUBMITTER: Liunardo JJ 

PROVIDER: S-EPMC11039241 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature