Mindfulness-based intervention reduce interference of negative stimuli to working memory in individuals with subclinical depression: A randomized controlled fMRI study.

ABSTRACT:

Background

Individuals with subclinical depression are prone to major depression and experience emotional responses and attentional biases to negative stimuli.

Method

In a randomized controlled study (N = 42) using functional magnetic resonance imaging (fMRI), we examined the neurocognitive mechanisms behind mindfulness-based cognitive therapy (MBCT) combining loving-kindness meditation (LKM) on a group with subclinical depression compared with the relaxation group across emotional face n-back (EFNBACK) tasks and resting state. We also collected behavioral and self-reported data to confirm neurocognitive results.

Results

During EFNBACK, the MBCT+LKM group showed greater activation in the left lingual gyrus and right inferior lateral occipital cortex. During res

SUBMITTER: Hong C 

PROVIDER: S-EPMC11039314 | biostudies-literature | 2024 Apr-Jun

REPOSITORIES: biostudies-literature