Infection risk reduction with povidone-iodine rectal disinfection prior to transrectal prostate biopsy: an updated systematic review and meta-analysis.

ABSTRACT:

Background

To prevent infectious complications after transrectal ultrasound-guided prostate biopsy (TRUS-PB), some studies have investigated the efficacy of rectal disinfection using povidone-iodine (PI) and antibiotic prophylaxis (AP).

Objective

To summarize available data and compare the efficacy of rectal disinfection using PI with non-PI methods prior to TRUS-PB.

Evidence acquisition

Three databases were queried through November 2023 for randomized controlled trials (RCTs) analyzing patients who underwent TRUS-PB. We compared the effectiveness of rectal disinfection between PI groups and non-PI groups with or without AP. The primary outcomes of interest were the rates of overall infectious complications, fever, and sepsis. Subgroups analyses were conducted to asse

SUBMITTER: Tsuboi I 

PROVIDER: S-EPMC11039496 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature