Changes in Sleep Patterns, Genetic Susceptibility, and Incident Cardiovascular Disease in China.

ABSTRACT:

Importance

The associations of changes in sleep patterns with incident cardiovascular disease (CVD) are not fully elucidated, and whether these associations are modified by genetic susceptibility remains unknown.

Objectives

To investigate the associations of 5-year changes in sleep patterns with incident CVD and whether genetic susceptibility modifies these associations.

Design, setting, and participants

This prospective cohort study of the Dongfeng-Tongji cohort was conducted from 2008 to 2018 in China. Eligible participants included those with complete sleep information at baseline survey (2008-2010) and the first follow-up survey (2013); participants who had no CVD or cancer in 2013 were prospectively assessed until 2018. Statistical analysis was performed in Novem

SUBMITTER: Diao T 

PROVIDER: S-EPMC11040405 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature