The effect of COVID-19 vaccine to the Omicron variant in children and adolescents: a systematic review and meta-analysis.

ABSTRACT:

Background

Omicron (B.1.1.529), a variant of SARS-CoV-2, has emerged as a dominant strain in COVID-19 pandemic. This development has raised concerns about the effectiveness of vaccination to Omicron, particularly in the context of children and adolescents. Our study evaluated the efficacy of different COVID-19 vaccination regimens in children and adolescents during the Omicron epidemic phase.

Methods

We searched PubMed, Cochrane, Web of Science, and Embase electronic databases for studies published through March 2023 on the association between COVID-19 vaccination and vaccine effectiveness (VE) against SARS-CoV-2 infection in children and adolescents at the Omicron variant period. The effectiveness outcomes included mild COVID-19 and severe COVID-19. This study followed the

SUBMITTER: Lu W 

PROVIDER: S-EPMC11041831 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature