Milestoning estimators of dissipation in systems observed at a coarse resolution.

ABSTRACT: Many nonequilibrium, active processes are observed at a coarse-grained level, where different microscopic configurations are projected onto the same observable state. Such "lumped" observables display memory, and in many cases, the irreversible character of the underlying microscopic dynamics becomes blurred, e.g., when the projection hides dissipative cycles. As a result, the observations appear less irreversible, and it is very challenging to infer the degree of broken time-reversal symmetry. Here we show, contrary to intuition, that by ignoring parts of the already coarse-grained state space we may-via a process called milestoning-improve entropy-production estimates. We present diverse examples where milestoning systematically renders observations "closer to underlying microscopic dyna

SUBMITTER: Blom K 

PROVIDER: S-EPMC11047069 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature