Human nasal microbiota shifts in healthy and chronic respiratory disease conditions.

ABSTRACT:

Background

An increasing number of studies investigate various human microbiotas and their roles in the development of diseases, maintenance of health states, and balanced signaling towards the brain. Current data demonstrate that the nasal microbiota contains a unique and highly variable array of commensal bacteria and opportunistic pathogens. However, we need to understand how to harness current knowledge, enrich nasal microbiota with beneficial microorganisms, and prevent pathogenic developments.

Results

In this study, we have obtained nasal, nasopharyngeal, and bronchoalveolar lavage fluid samples from healthy volunteers and patients suffering from chronic respiratory tract diseases for full-length 16 S rRNA sequencing analysis using Oxford Nanopore Technologies. Demogra

SUBMITTER: Konovalovas A 

PROVIDER: S-EPMC11055347 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature