[11C]-methionine positron emission tomography in the evaluation of pediatric low-grade gliomas.

ABSTRACT:

Background

[¹¹C]-Methionine positron emission tomography (PET; [¹¹C]-MET-PET) is principally used for the evaluation of brain tumors in adults. Although amino acid PET tracers are more commonly used in the evaluation of pediatric brain tumors, data on [¹¹C]-MET-PET imaging of pediatric low-grade gliomas (pLGG) is scarce. This study aimed to investigate the roles of [¹¹C]-MET-PET in the evaluation of pLGGs.

Methods

Eighteen patients with newly diagnosed pLGG and 26 previously treated pLGG patients underwent [¹¹C]-MET-PET met the inclusion and exclusion criteria. Tumor-to-brain uptake ratio (TBR) and metabolic tumor volumes were assessed for diagnostic performances (newly diagnosed, 15; previously treated 26), change with

SUBMITTER: Kim EY 

PROVIDER: S-EPMC11055465 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature