Carbapenemase genes in clinical and environmental isolates of Acinetobacter spp. from Quito, Ecuador.

ABSTRACT: Carbapenem-resistant Acinetobacter spp. is associated with nosocomial infections in intensive care unit patients, resulting in high mortality. Although Acinetobacter spp. represent a serious public health problem worldwide, there are a few studies related to the presence of carbapenemases in health care facilities and other environmental settings in Ecuador. The main aim of this study was to characterize the carbapenem-resistant Acinetobacter spp. isolates obtained from four hospitals (52) and from five rivers (27) close to Quito. We used the disc diffusion and EDTA sinergy tests to determine the antimicrobial susceptibility and the production of metallo β-lactamases, respectively. We carried out a multiplex PCR of gyrB gene and the sequencing of partial rpoB

SUBMITTER: Sotomayor N 

PROVIDER: S-EPMC11056107 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature