Patient understanding of pharmacogenomic test results in clinical care.

ABSTRACT:

Objective

Previous research has not objectively assessed patients' comprehension of their pharmacogenomic test results. In this study we assessed understanding of patients who had undergone cytochrome P450 2C19 (CYP2C19) pharmacogenomic testing.

Methods

31 semi-structured interviews with patients who underwent CYP2C19 testing after cardiac catheterization and had been sent a brochure, letter, and wallet card explaining their results. Answers to Likert and binary questions were summarized with descriptive statistics. Qualitative data were analyzed using a grounded theory approach, with particular focus on categorization.

Results

No participants knew the name of the gene tested or their metabolizer status. Seven participants (23%) knew whether the testing identified any

SUBMITTER: Doyle TA 

PROVIDER: S-EPMC11058699 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature