Magnetic Seizure Therapy vs Modified Electroconvulsive Therapy in Patients With Bipolar Mania: A Randomized Clinical Trial.

ABSTRACT:

Importance

Bipolar mania is a common disabling illness. Electroconvulsive therapy (ECT) is an effective treatment for patients with severe mania, though it is limited by the risk of cognitive adverse effects. Magnetic seizure therapy (MST) as an alternative treatment to ECT for bipolar mania has not yet been reported.

Objective

To compare the effectiveness and cognitive adverse effects of MST and ECT in bipolar mania.

Design, setting, and participants

This randomized clinical trial was conducted at the Shanghai Mental Health Center from July 1, 2017, through April 26, 2021. Forty-eight patients with bipolar mania were recruited and randomly allocated to receive MST or ECT. The data analysis was performed from June 5, 2021, through August 30, 2023.

Interventions

SUBMITTER: Chen S 

PROVIDER: S-EPMC11059045 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature