A randomised clinical trial of awake prone positioning in COVID-19 suspects with acute hypoxemic respiratory failure.

ABSTRACT:

Background

Awake prone position (APP) has been reported to improve oxygenation in patients with COVID-19 disease and to reduce the requirement for invasive mechanical ventilation for patients requiring support with high flow nasal cannula. There is conflicting data for patients requiring lower-level oxygen support.

Research question

Does APP reduce escalation of oxygen support in COVID-19 patients requiring supplementary oxygen?The primary outcome was defined as an escalation of oxygen support from simple supplementary oxygen (NP, HM, NRB) to NIV (CPAP or BiPAP), HFNC or IMV; OR from NIV (CPAP or BiPAP) or HFNC to IMV by day30.

Study design

Two center, prospective, non-blind, randomised controlled trial. Patients with confirmed or su

SUBMITTER: Harris TRE 

PROVIDER: S-EPMC11059337 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature