Clinical validation of a capnodynamic method for measuring end-expiratory lung volume in critically ill patients.

ABSTRACT:

Rationale

End-expiratory lung volume (EELV) is reduced in mechanically ventilated patients, especially in pathologic conditions. The resulting heterogeneous distribution of ventilation increases the risk for ventilation induced lung injury. Clinical measurement of EELV however, remains difficult.

Objective

Validation of a novel continuous capnodynamic method based on expired carbon dioxide (CO₂) kinetics for measuring EELV in mechanically ventilated critically-ill patients.

Methods

Prospective study of mechanically ventilated patients scheduled for a diagnostic computed tomography exploration. Comparisons were made between absolute and corrected EELVCO₂ values, the latter accounting for the amount of CO₂ dissolved in lung tissue, with

SUBMITTER: Sanchez Giralt JA 

PROVIDER: S-EPMC11059761 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature