Day-night pattern of acute ST-segment elevation myocardial infarction onset in patients with obstructive sleep apnea.

ABSTRACT:

Study objectives

Obstructive sleep apnea (OSA) is associated with acute nocturnal hemodynamic and neurohormonal abnormalities that may increase the risk of coronary events, especially during the nighttime. This study sought to investigate the day-night pattern of acute ST-segment elevation myocardial infarction (STEMI) onset in patients with OSA and its impact on cardiovascular adverse events.

Methods

We prospectively enrolled 397 patients with STEMI, for which the time of onset of chest pain was clearly identified. All participants were categorized into non-OSA (n = 280) and OSA (n = 117) groups. The association between STEMI onset time and major adverse cardiovascular and cerebrovascular events was estimated by Cox proportional hazards regression.

Results

STEMI onse

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11063706 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature