Clinical and genomic characteristics of IMP-producing <i>Enterobacter cloacae</i> complex and <i>Klebsiella pneumoniae</i>.

ABSTRACT: Carbapenemase-producing Enterobacterales (CPEs) are one of the top priority antimicrobial-resistant pathogens. Among CPEs, those producing acquired metallo-β-lactamases (MBLs) are considered particularly problematic as few agents are active against them. Imipenemase (IMP) is the most frequently encountered acquired MBL in Japan, but comprehensive assessment of clinical and microbiological features of IMP-producing Enterobacterales infection remains scarce. Here, we retrospectively evaluated 62 patients who were hospitalized at a university hospital in Japan and had IMP-producing Enterobacterales from a clinical culture. The isolates were either Enterobacter cloacae complex or Klebsiella pneumoniae, and most of them were isolated from sputum. The majority

SUBMITTER: Suzuki D 

PROVIDER: S-EPMC11064536 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature