Biases and limitations in observational studies of Long COVID prevalence and risk factors: A rapid systematic umbrella review.

ABSTRACT:

Background

Observational studies form the foundation of Long COVID knowledge, however combining data from Long COVID observational studies has multiple methodological challenges. This umbrella review synthesizes estimates of Long COVID prevalence and risk factors as well as biases and limitations in the primary and review literatures.

Methods and findings

A systematic literature search was conducted using multiple electronic databases (PubMed, EMBASE, LitCOVID) from Jan 1, 2019 until June 9, 2023. Eligible studies were systematic reviews including adult populations assessed for at least one Long COVID symptom four weeks or more after SARS-CoV-2 infection. Overall and subgroup prevalence and risk factors as well as risk of bias (ROB) assessments were extracted and descriptive

SUBMITTER: Hua MJ 

PROVIDER: S-EPMC11065234 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature