Velocity-selective arterial spin labeling perfusion measurements in 2nd trimester human placenta with varying BMI.

ABSTRACT:

Introduction

Proper placental development is crucial to fetal health but is challenging to functionally assess non-invasively and is thus poorly characterized in populations. Body mass index (BMI) has been linked with adverse outcomes, but the causative mechanism is uncertain. Velocity-selective arterial spin labeling (VS-ASL) MRI provides a method to non-invasively measure placental perfusion with robustness to confounding transit time delays. In this study, we report on the measurement of perfusion in the human placenta in early pregnancy using velocity-selective arterial spin labeling (VS-ASL) MRI, comparing non-obese and obese participants.

Methods

Participants (N = 97) undergoing routine prenatal care were recruited and imaged with structural and VS-ASL perfusion MRI at

SUBMITTER: Seiter D 

PROVIDER: S-EPMC11065564 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature