Retrospective Validation of a Computerized Physiologic Equation to Predict Minute Ventilation Needs in Critically Ill Children.

ABSTRACT:

Objectives

Mechanical ventilation (MV) is pervasive among critically ill children. We sought to validate a computerized physiologic equation to predict minute ventilation requirements in children and test its performance against clinician actions in an in silico trial.

Design

Retrospective, electronic medical record linkage, cohort study.

Setting

Quaternary PICU.

Patients

Patients undergoing invasive MV, serial arterial blood gas (ABG) analysis within 1-6 hours, and pharmacologic neuromuscular blockade (NMB).

Measurements and main results

ABG values were filtered to those occurring during periods of NMB. Simultaneous ABG and minute ventilation data were linked to predict serial Pa co2 and pH values using previously published physiologic equations. There

SUBMITTER: Pelletier JH 

PROVIDER: S-EPMC11065608 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature