Establishment of glioma prognosis nomogram based on the function of meox1 in promoting the progression of cancer.

ABSTRACT:

Background

Gliomas stand out as highly predominant malignant nervous tumors and are linked to adverse treatment outcomes and short survival periods. Current treatment options are limited, emphasizing the need to identify effective therapeutic targets. The heterogeneity of tumors necessitates a personalized treatment approach with an effective grouping system. Meox1 has been implicated in promoting tumor progression in diverse cancers; nonetheless, its role in gliomas remains unelucidated.

Material/methods

Utilized immunohistochemistry to assess the expression of Meox1 protein in glioma tissues. Proliferation and invasion assays were conducted on wild-type and meox1-overexpressed glioma cells using the CCK8 and Transwell assays, respectively. The expression levels of m

SUBMITTER: Pan P 

PROVIDER: S-EPMC11066332 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature