DTI-MR fingerprinting for rapid high-resolution whole-brain T₁ , T₂ , proton density, ADC, and fractional anisotropy mapping.

ABSTRACT:

Purpose

This study aims to develop a high-efficiency and high-resolution 3D imaging approach for simultaneous mapping of multiple key tissue parameters for routine brain imaging, including T₁ , T₂ , proton density (PD), ADC, and fractional anisotropy (FA). The proposed method is intended for pushing routine clinical brain imaging from weighted imaging to quantitative imaging and can also be particularly useful for diffusion-relaxometry studies, which typically suffer from lengthy acquisition time.

Methods

To address challenges associated with diffusion weighting, such as shot-to-shot phase variation and low SNR, we integrated several innovative data acquisition and reconstruction techniques. Specifically, we used M1-compensated diffusion gradients, card

SUBMITTER: Cao X 

PROVIDER: S-EPMC11068310 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature