Proportion of Time Covered by Hepatocellular Carcinoma Surveillance in Patients With Cirrhosis.

ABSTRACT:

Introduction

Hepatocellular carcinoma (HCC) surveillance is associated with improved early tumor detection, but effectiveness is limited by underuse. We characterized adherence to HCC surveillance using proportion of time covered (PTC) and estimated its association with clinical outcomes among patients with cirrhosis.

Methods

We conducted a retrospective cohort study of patients diagnosed with HCC between January 2008 and December 2022 at 2 large US health systems. We characterized PTC by imaging in the 12 and 24 months before HCC diagnosis. We used multivariable logistic and Cox regression analyses to assess the association between PTC and early HCC detection, receipt of curative treatment, and overall survival.

Results

Among 2,027 patients with HCC, 331 (51.4% Barce

SUBMITTER: Daher D 

PROVIDER: S-EPMC11068493 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature