Chromosome-Y haplogroups in Asturias (Northern Spain) and their association with severe COVID-19.

ABSTRACT: The main objective of this study was to determine whether the common Y-haplogroups were be associated with the risk of developing severe COVID-19 in Spanish male. We studied 479 patients who required hospitalization due to COVID-19 and 285 population controls from the region of Asturias (northern Spain), They were genotyped for several polymorphisms that define the common European Y-haplogroups. We compared the frequencies between patients and controls aged ≤ 65 and >65 years. There were no different haplogroup frequencies between the two age groups of controls. Haplogroup R1b was less common in patients aged ≤65 years. Haplogroup I was more common in the two patient´s groups compared to controls (p = 0.02). Haplogroup R1b was significantly more frequent among hypertensive patients, withou

SUBMITTER: Gonzalez-Fernandez M 

PROVIDER: S-EPMC11069473 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature